Histone 3 anticorps (C-Term)

N° du produit ABIN1118467

N° du produit (Fournisseur): 100-401-e81

Cet anticorps Lapin Polyclonal détecte spécifiquement Histone 3 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Histone 3 anticorps (C-Term) (ABIN1118467)

Antigène: Histone 3 (H3) (Histone H3 (H3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Histone 3 anticorps

Épitope: C-Term

N° du produit (Fournisseur): 100-401-e81

Fournisseur: Rockland

Fonction: Histone H3 Antibody

Réactivité croisée (Details): Anti-Histone H3 is directed against the human histone 3 protein.

Attributs du produit: Synonyms: rabbit anti-Histone H3 antibody, Histone H3.1, H3F, H3FA, H3FB, H3FL, H3FL, H3FC, H3FD, H3FI, H3FH, H3FK, H3FF, H3FJ, Histone 3 Antibody

Purification: The product was prepared from monospecific antiserum by delipidation and defibrination.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Anti-Histone-3 was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to the c-terminus region of human histone-3.

Immunogen Type: Conjugated Peptide

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 1:100

Application Note: Histone H3 antibody has been tested for use in ELISA, IHC, and western blot. For western blots expect a band of approximately 15.4 kDa in size corresponding to the Histone 3 protein. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1:2000

ELISA Dilution: 1:10000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 83 mg/ml

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store H3 Antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-Histone 3 (ABIN1118467)

Rivera-Casas, Gonzalez-Romero, Garduño, Cheema, Ausio, Eirin-Lopez: "Molecular and Biochemical Methods Useful for the Epigenetic Characterization of Chromatin-Associated Proteins in Bivalve Molluscs." dans: Frontiers in physiology, Vol. 8, pp. 490, (2017) (PubMed).

Détails sur Histone 3

Antigène: Histone 3 (H3) (Histone H3 (H3))

Autre désignation: Histone H3

Sujet: Background: Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Histone proteins are highly post-translationally modified with Histone H3 being the most extensively modified of the five histones. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histone H3 Antibody is ideal for investigators involved in Cell Signaling, Epigenetics, Nuclear Signaling research and Signal Transduction research.

ID gène: 8350

NCBI Accession: NP_003520

UniProt: P68431